Fridericia Formula:
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The Fridericia formula is a method for correcting the QT interval for heart rate, recommended for general use. It provides a more accurate assessment of ventricular repolarization than other correction formulas in many clinical scenarios.
The calculator uses the Fridericia formula:
Where:
Explanation: The formula accounts for the physiological relationship between heart rate and QT interval duration, with the cube root providing optimal correction across various heart rates.
Details: Accurate QTc calculation is crucial for assessing cardiac repolarization abnormalities, identifying risk of arrhythmias, monitoring drug effects on cardiac conduction, and evaluating patients with potential long QT syndrome.
Tips: Enter QT interval in milliseconds and heart rate in beats per minute. Both values must be positive numbers. The RR interval is automatically calculated from the heart rate input.
Q1: Why use Fridericia formula instead of Bazett?
A: Fridericia formula provides better correction across a wider range of heart rates and is less likely to overcorrect at high heart rates compared to Bazett's formula.
Q2: What are normal QTc values?
A: Normal QTc is generally <450 ms for men and <470 ms for women. Values above these thresholds may indicate prolonged QT interval.
Q3: When should QTc be measured?
A: QTc should be measured in standard 12-lead ECGs, particularly when evaluating patients for arrhythmia risk, monitoring QT-prolonging medications, or assessing patients with syncope or family history of sudden cardiac death.
Q4: Are there limitations to Fridericia formula?
A: While superior to Bazett, Fridericia may still have limitations at extreme heart rates. In some cases, linear regression formulas or patient-specific correction may be preferred.
Q5: Should different formulas be used in specific populations?
A: Some populations (e.g., children, athletes) may benefit from population-specific correction formulas. Fridericia is generally recommended for adult clinical use.