QTc Calculation Formula:
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The QTc (Corrected QT Interval) calculation adjusts the measured QT interval for heart rate using Bazett's formula. This provides a standardized measure of ventricular repolarization that can be compared across different heart rates.
The calculator uses Bazett's formula:
Where:
Normal Ranges:
Details: QTc prolongation is associated with increased risk of ventricular arrhythmias, particularly torsades de pointes. Accurate QTc measurement is essential for cardiac risk assessment and medication safety monitoring.
Tips: Enter QT interval in milliseconds, heart rate in beats per minute, and select gender. All values must be valid (QT > 0, HR > 0).
Q1: Why correct QT interval for heart rate?
A: The QT interval naturally shortens with increasing heart rate. Correction allows comparison of QT values across different heart rates.
Q2: What is considered a dangerously prolonged QTc?
A: QTc > 500 ms is associated with significantly increased risk of torsades de pointes and requires immediate attention.
Q3: Are there alternative correction formulas?
A: Yes, other formulas include Fridericia's (QTc = QT/RR1/3) and Framingham (QTc = QT + 0.154*(1-RR)), but Bazett's is most commonly used.
Q4: When should QTc be measured?
A: QTc should be measured when starting medications that may prolong QT interval, in patients with syncope, or with family history of sudden cardiac death.
Q5: What factors can affect QTc measurement?
A: Electrolyte imbalances, medications, myocardial ischemia, and autonomic nervous system activity can all affect QTc duration.