Bazett's Formula:
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The QTc (Corrected QT) interval calculation using Bazett's formula adjusts the measured QT interval for heart rate, providing a standardized measure of ventricular repolarization that can be compared across different heart rates.
The calculator uses Bazett's formula:
Where:
Explanation: The formula corrects the QT interval for heart rate by dividing by the square root of the RR interval, providing a rate-independent measure of ventricular repolarization.
Details: Accurate QTc calculation is crucial for assessing risk of arrhythmias, monitoring drug effects (especially those that prolong QT interval), and evaluating cardiac repolarization abnormalities.
Tips: Enter QT interval in milliseconds and heart rate in beats per minute. Both values must be positive numbers.
Q1: What is a normal QTc value?
A: Normal QTc values are typically <440 ms for men and <460 ms for women. Values above these may indicate prolonged QT interval.
Q2: Why is QTc prolongation dangerous?
A: QTc prolongation increases the risk of life-threatening ventricular arrhythmias, particularly torsades de pointes.
Q3: Are there limitations to Bazett's formula?
A: Yes, Bazett's formula tends to overcorrect at high heart rates and undercorrect at low heart rates. Other formulas (Fridericia, Framingham) may be used in specific situations.
Q4: When should QTc be measured?
A: QTc should be measured when starting medications known to prolong QT interval, in patients with syncope or arrhythmias, and in those with family history of sudden cardiac death.
Q5: How should multiple QT measurements be handled?
A: When multiple measurements are available, use the average of several beats (usually 3-5) from the same lead for more accurate results.