QTc Correction Formulas:
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QTc (corrected QT interval) is a heart rate-adjusted QT interval that allows comparison of QT values across different heart rates. It's essential for assessing cardiac repolarization and detecting potential arrhythmia risks.
The calculator uses multiple correction formulas:
Where:
Explanation: Different formulas provide varying degrees of accuracy across different heart rate ranges and patient populations.
Details: Accurate QTc calculation is crucial for detecting prolonged QT syndrome, assessing drug-induced QT prolongation, and evaluating cardiac safety in clinical practice and research.
Tips: Enter QT interval in milliseconds, heart rate in bpm, and select the desired correction formula. All values must be valid (QT > 0, HR > 0).
Q1: Which formula is most accurate?
A: Bazett is most commonly used but tends to overcorrect at high heart rates. Fridericia and Framingham are often more accurate across wider heart rate ranges.
Q2: What are normal QTc values?
A: Normal QTc is typically <440 ms for men and <460 ms for women. Values >500 ms are associated with increased arrhythmia risk.
Q3: When should I use different formulas?
A: Bazett is standard for clinical use. Fridericia is preferred in research settings. Framingham and Hodges may be better for extreme heart rates.
Q4: How is QT interval measured?
A: QT is measured from the start of the Q wave to the end of the T wave on ECG, preferably in lead II or V5.
Q5: What causes prolonged QTc?
A: Medications, electrolyte imbalances, congenital syndromes, myocardial ischemia, and neurological disorders can prolong QTc.