QTc Formula:
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QTc (Corrected QT Interval) calculation adjusts the measured QT interval for heart rate using Bazett's formula. This provides a standardized measure of ventricular repolarization that can be compared across different heart rates.
The calculator uses Bazett's formula:
Where:
Explanation: The formula corrects the QT interval for heart rate variations, providing a standardized measure of ventricular repolarization time.
Details: QTc measurement is crucial for assessing risk of arrhythmias, particularly torsades de pointes. Prolonged QTc intervals may indicate increased risk of sudden cardiac death and require careful monitoring and potential intervention.
Tips: Enter QT interval in milliseconds and heart rate in beats per minute. Both values must be positive numbers. QxMD uses Bazett formula by default for QTc calculation.
Q1: Why use Bazett's formula?
A: Bazett's formula is the most widely used and clinically accepted method for QTc calculation, though it may overcorrect at very high heart rates.
Q2: What are normal QTc values?
A: Normal QTc is typically <440 ms for men and <460 ms for women. Values above these thresholds may indicate prolonged QT syndrome.
Q3: When should QTc be measured?
A: QTc should be measured in patients taking medications that may prolong QT interval, those with family history of sudden cardiac death, or when arrhythmias are suspected.
Q4: Are there limitations to Bazett's formula?
A: Yes, Bazett's formula tends to overcorrect at high heart rates and undercorrect at low heart rates. Alternative formulas like Fridericia may be used in specific cases.
Q5: How accurate is this calculation?
A: The calculation provides a good estimate for clinical purposes, but manual measurement of QT interval from ECG should be performed by trained medical professionals for accurate assessment.