Fridericia Formula:
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The QTc (corrected QT interval) calculation using Fridericia's formula is particularly useful in atrial fibrillation (AFib) as it accounts for heart rate variability by using the average RR interval over 10 beats. This provides a more accurate correction of the QT interval for heart rate.
The calculator uses Fridericia's formula:
Where:
Explanation: The formula corrects the QT interval for heart rate using a cube root correction, which is particularly suitable for atrial fibrillation with variable RR intervals.
Details: Accurate QTc calculation is crucial for assessing cardiac repolarization, identifying risk of arrhythmias (particularly torsades de pointes), and guiding medication decisions in patients with atrial fibrillation.
Tips: Enter QT interval in milliseconds and heart rate in beats per minute. Use the average RR interval over 10 beats in atrial fibrillation for most accurate results. All values must be valid (QT > 0, HR > 0).
Q1: Why use Fridericia's formula in atrial fibrillation?
A: Fridericia's formula with average RR interval over multiple beats provides more stable QTc values in AFib where RR intervals vary significantly from beat to beat.
Q2: What are normal QTc values?
A: Normal QTc is generally <450 ms for men and <460 ms for women. Values >500 ms indicate high risk for torsades de pointes.
Q3: How many beats should be averaged in AFib?
A: Typically 10 consecutive beats are averaged to calculate the mean RR interval for most accurate QTc correction in atrial fibrillation.
Q4: When is QTc measurement most important?
A: Particularly important when starting medications that prolong QT interval, in patients with syncope, or when assessing arrhythmia risk.
Q5: Are there other QT correction formulas?
A: Yes, Bazett's formula (QT/√RR) is commonly used but tends to overcorrect at high heart rates. Fridericia's is often preferred in AFib.