Bazett's Formula:
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QTc (Corrected QT interval) is a heart rate-adjusted QT interval measurement. Bazett's formula is commonly used to correct QT interval for heart rate, providing a standardized measure for cardiac repolarization assessment.
The calculator uses Bazett's formula:
Where:
Explanation: The formula adjusts the QT interval for heart rate variations, providing a standardized measure that accounts for the inverse relationship between heart rate and QT duration.
Details: QTc measurement is crucial for assessing cardiac repolarization abnormalities. Prolonged QTc intervals are associated with increased risk of ventricular arrhythmias and sudden cardiac death.
Tips: Enter QT interval in milliseconds and heart rate in beats per minute. Both values must be positive numbers. The calculator will compute the corrected QT interval using Bazett's formula.
Q1: What is a normal QTc value?
A: Normal QTc values are typically <440 ms for men and <460 ms for women. Values above these thresholds may indicate prolonged QT syndrome.
Q2: Why use Bazett's formula?
A: Bazett's formula is the most widely used and clinically validated method for QT correction, though it may overcorrect at very high heart rates.
Q3: When should QTc be measured?
A: QTc should be measured in patients taking medications that may prolong QT interval, in those with syncope or family history of sudden death, and in routine cardiac assessments.
Q4: Are there limitations to Bazett's formula?
A: Yes, it tends to overcorrect at high heart rates and undercorrect at low heart rates. Other formulas (Fridericia, Framingham) may be used in specific situations.
Q5: What factors can affect QT interval?
A: Medications, electrolyte imbalances, cardiac conditions, autonomic nervous system activity, and genetic factors can all influence QT interval duration.