QTc Formula:
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The QTc (corrected QT interval) calculation adjusts the measured QT interval for heart rate using Bazett's formula. This correction is essential for accurate assessment of ventricular repolarization and detection of potential arrhythmia risks.
The calculator uses Bazett's formula:
Where:
Normal Values: <440 ms for men, <460 ms for women. Prolonged QTc may indicate increased risk of ventricular arrhythmias.
Details: Accurate QTc calculation is crucial for assessing cardiac repolarization abnormalities, monitoring drug effects on cardiac conduction, and identifying patients at risk for torsades de pointes and other ventricular arrhythmias.
Tips: Enter the measured QT interval in milliseconds, heart rate in beats per minute, and select gender. Ensure accurate QT measurement from the start of Q wave to the end of T wave.
Q1: Why correct QT for heart rate?
A: The QT interval naturally shortens with increasing heart rate. Correction allows comparison of QT values across different heart rates.
Q2: What are the clinical implications of prolonged QTc?
A: Prolonged QTc (>440 ms men, >460 ms women) increases risk of ventricular tachyarrhythmias, particularly torsades de pointes.
Q3: Are there alternative correction formulas?
A: Yes, other formulas include Fridericia's (QTc = QT/RR1/3) and Framingham (QTc = QT + 0.154*(1-RR)), but Bazett's is most commonly used.
Q4: When should QTc be measured?
A: QTc should be monitored when starting medications that affect cardiac repolarization, in patients with electrolyte imbalances, or with personal/family history of arrhythmias.
Q5: What factors can affect QTc measurement?
A: Electrolyte abnormalities (especially potassium), medications, myocardial ischemia, and autonomic nervous system activity can all affect QTc duration.