Framingham Linear Formula:
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The Framingham QTc formula is a linear regression equation used to correct the QT interval for heart rate. It provides a more accurate assessment of ventricular repolarization by accounting for variations in heart rate.
The calculator uses the Framingham linear formula:
Where:
Explanation: The formula adjusts the measured QT interval based on the RR interval to provide a heart rate-corrected QT value that can be compared across different heart rates.
Details: Accurate QTc calculation is crucial for assessing cardiac repolarization abnormalities, identifying risk of arrhythmias, and monitoring drug effects on cardiac conduction.
Tips: Enter QT interval in milliseconds and heart rate in beats per minute. Both values must be valid positive numbers.
Q1: Why correct QT interval for heart rate?
A: The QT interval naturally shortens with increasing heart rate. Correction allows comparison of QT values across different heart rates.
Q2: What are normal QTc values?
A: Normal QTc is typically <440 ms for men and <460 ms for women. Values above these may indicate prolonged QT syndrome.
Q3: When should QTc be measured?
A: QTc should be measured during electrocardiogram (ECG) interpretation, especially when assessing arrhythmia risk or monitoring QT-prolonging medications.
Q4: Are there other QT correction formulas?
A: Yes, other formulas include Bazett's formula (QTc = QT/√RR) and Fridericia's formula (QTc = QT/∛RR). Framingham is considered more accurate at extreme heart rates.
Q5: What clinical conditions affect QTc?
A: Various conditions including electrolyte imbalances, medications, congenital long QT syndrome, and myocardial ischemia can affect QTc intervals.